Fritsch was born in Essen, Germany, in 1956. She represented Germany in the 1995 Venice Biennale and has had one-person exhibitions at the Kunstmuseum, Basel; the San Francisco Museum of Modern Art; Tate Modern, London; and K21, Düsseldorf. A retrospective exhibition of Fritsch’s work was held in 2009 at the Kunstmuseum Zürich which traveled to the Deichtorhallen Hamburg. Most recently, the city of London and The Royal Society for the Encouragement of Arts commissioned Fritsch to build a sculpture “Hahn / Cock” to be displayed on the fourth plinth in the northwest corner of Trafalgar Square. Fritsch has been represented by Matthew Marks Gallery since 1994. She lives and works in Düsseldorf.